MIEP
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  • CD4+ T cell model

    MIEP is studying CD4+ T cell heterogeneity, plasticity and differentiation by using mathematical and computational modeling in combination with immunology experimentation and single cell analyses.


  • Integrative Modeling

    MIEP’s translational medicine research integrates computational modeling with novel experimental approaches in an innovative product development pipeline leading to the characterization of novel mechanisms of immune modulation and development of new therapies.


  • Education

    Were you unable to attend Modeling Mucosal Immunity (MMI) Summer School Program and Symposium hosted by the Center for Modeling Immunity to Enteric Pathogens at Virginia Tech? Click here to see what you missed! Tutorials and a new Books based on Summer School materials are now available


  • Helicobacter pylori

    MIEP was the first to demonstrate the strong cytotoxic CD8+ T cell responses during Helicobacter pylori infection in pigs, further confirming the role of H. pylori as an intracellular pathogen.


  • NIMML Highlights

    Innovative NIMML Translational Medicine approaches used to tackle challenges in infectious, immune-mediated and chronic inflammatory disease research.


  • Apply to be a USP student

    ​Click here to submit your application online.

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© 2000 - 2025 NIMML Institute


  • Clinical
    • Clinical Development (Phase I-IV)
  • Pig Models
    • Neonatal pig model
    • Inflammatory bowel disease
    • Novel Pig Model of H. pylori
  • Media & Press Kit
    • Mission, Vision, Values
    • History
    • Quick Facts
    • Strategic Initiatives
  • ENISI Helicobacter Pylori Model
    • Sensitivity Analysis
    • Cell Movement Modeling
  • CDiff Computational Model Archive
    • Mucosal Immune Responses
    • PPAR γ and miRNA
  • EAEC Computational Model
    • Mucosal Immune Responses
    • T Cell Response
    • Epithelial Cell Responses
  • Macrophage Computational Model Archive
    • April 2012
    • Jan 2012
    • Oct 2011
  • COPASI Helicobacter Pylori Computational Model Archive
    • May 2012
    • April 2012
    • Jan 2012
    • Sep 2011
  • CD4+ T Cell Model Archive
    • Feb 2014
    • October 2012
    • August 2012
    • April 2012
    • Jan 2012
    • Sep 2011
    • June 2011
    • March 2011
  • Immunology
    • Helicobacter pylori
    • CD4+ T cell differentiation
    • Human Studies
    • Enteroaggregative E. coli
  • Animal Models
    • Type 2 Diabetes
    • Clostridium dificile infection
    • Influenza
    • Inflammatory bowel disease
    • Helicobacter pylori
    • Pig Models
    • Murine Models
  • Infectious Diseases
    • Helicobacter pylori
    • Clostridium difficile
    • Enteroaggregative E. coli
  • Immune Mediated Diseases
    • Novel IBD Interventions
  • Nutritional Immunology
    • Novel IBD Interventions
    • Phytochemicals
    • Dietary Lipids
    • Prebiotics and Probiotics
  • Drug Development
    • Host-targeted Therapeutics
    • Translational Medicine
  • Data
    • Modeling NLRX1 response to H.pylori
    • Modeling Clostridium difficile Immune Response
    • EAEC Zinc Deficiency
    • IL-21 in the Gastric Mucosa
    • Novel Pig Model
    • CD4+ T Cells
    • Modeling H. pylori Immune Response
    • Clostridium difficile
    • Enteroaggregative Escherichia coli
    • ENISI V0.9 in silico experiments
  • Computational Models
    • Inflammatory bowel disease
    • CD4+ T Cell Model
    • Host Responses to H. pylori
    • Host Responses to EAEC
    • Host Responses to C. difficile
    • Macrophages
  • Tools
    • CMS
    • CellDesigner
    • ENISI Suite
    • COPASI Suite
    • Galaxy
    • LabKey
    • RedCap
    • Intranet
    • CellPublisher
  • Projects
    • Alternate Preclinical Models Of Enteric Infection
    • Modeling Infectious Disease Kinetics (MIDK-cWMD)
  • Immunoinformatics
    • Computational Modeling
    • High Performance Computing
    • Transcriptomics
  • NIMML POLICIES
    • FCOI